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Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

ZHANG Xiaomei, JIANG Liangduo, ZHANG Wei, WU Jianjun, LU Xiangfeng

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 314-316 doi: 10.1007/s11684-008-0060-8

Abstract: The aim of this paper is to observe the effect of the Feixian Recipe on pulmonary fibrosis in rats.A rat model with pulmonary fibrosis was established by intratracheal injection of bleomycin.Feixian Recipe has a significant therapeutic effect on bleomycin-induced pulmonary fibrosis in rats.

Keywords： bleomycin     intratracheal injection     prednisone     collagen     bleomycin-induced pulmonary    

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mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway in pulmonaryfibrosis

Li Lu, Haiyan Zhu, Hailin Wang, Huaping Liang, Yayi Hou, Huan Dou

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 313-329 doi: 10.1007/s11684-020-0737-1

Abstract: The epithelial–mesenchymal transition (EMT) is involved in the pathogenesis of idiopathic pulmonary fibrosisThe present study investigates the role of HSM in mediating EMT during the development of pulmonary fibrosisHSM significantly inhibits bleomycin (BLM)-induced pulmonary fibrosis by blocking the EMT.

Keywords： epithelial−mesenchymal transition     H. sinensis mycelium     midkine     pulmonary fibrosis    

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Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 425-432 doi: 10.1007/s11684-013-0295-x

Abstract:

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality

Keywords： chronic obstructive pulmonary disease     heterogeneity     phenotype     genotype     prediction    

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Survey on deep learning for pulmonary medical imaging

Jiechao Ma, Yang Song, Xi Tian, Yiting Hua, Rongguo Zhang, Jianlin Wu

Frontiers of Medicine 2020, Volume 14, Issue 4,   Pages 450-469 doi: 10.1007/s11684-019-0726-4

Abstract: include classification, detection, and segmentation tasks on medical image analysis with respect to pulmonaryA comprehensive overview of these methods implemented on various lung diseases consisting of pulmonarynodule diseases, pulmonary embolism, pneumonia, and interstitial lung disease is also provided.

Keywords： deep learning     neural networks     pulmonary medical image     survey    

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Strategies for preventing peritoneal fibrosis in peritoneal dialysis patients: new insights based on

Zhen Zhang, Na Jiang, Zhaohui Ni

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 349-358 doi: 10.1007/s11684-017-0571-2

Abstract: morphologic and functional changes to the peritoneal membrane (PM), which is defined as peritoneal fibrosisInflammation and angiogenesis are key events during the pathogenesis of peritoneal fibrosis.This review discusses the pathophysiology of peritoneal fibrosis and recent research progress on key

Keywords： peritoneal dialysis     peritoneal fibrosis     inflammation     angiogenesis    

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Expression of integrin in hepatic fibrosis and intervention of resveratrol

Jianye WU, Chuanyong GUO, Jun LIU, Xuanfu XUAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 100-107 doi: 10.1007/s11684-009-0013-x

Abstract: The aim of this study was to explore the expression of integrin-β1 in different stages of hepatic fibrosisand intervention of resveratrol as well as the way by which integrin-β1 promoted hepatic fibrosis.Hepatic fibrosis models of male Sprague Dawley (SD) rats were created and intragastric administrationLiver function and pathological sections of each group in different stages of hepatic fibrosis was testedas the development of hepatic fibrosis.

Keywords： liver fibrosis     integrin-β1     resveratrol     tumor growth factor-β     tissue inhibitor of metalloproteinase-1    

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Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 445-455 doi: 10.1007/s11684-014-0378-3

Abstract: Whether and how it ameliorates cardiac fibrosis, a major cause of diastolic dysfunction and heart failureThe purpose of this study was to investigate the effects of PDE5 inhibitor on cardiac fibrosis.We assessed cardiac fibrosis and pathology in mice subjected to transverse aortic constriction (TAC).In control mice, 4 weeks of TAC induced significant cardiac dysfunction, cardiac fibrosis, and cardiacSildenafil treatment markedly prevented TAC-induced cardiac dysfunction, cardiac fibrosis and cardiac

Keywords： PDE5     cardiac fibrosis     TGF-β     CREB    

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Protein microspheres for pulmonary drug delivery

Yongda SUN,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 1,   Pages 82-86 doi: 10.1007/s11705-009-0307-1

Abstract: A new supercritical fluid (SCF) technique was developed for the preparation of microspheres for pulmonarywater, leading to a dry fine powder with good particle size distribution and near ideal morphology for pulmonary

Keywords： advanced engineering     improved     pressure     aqueous     technique    

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Treatment outcomes of pulmonary tuberculosis in the past decade in the mainland of China: a meta-analysis

Xiangwei Li, Yu Yang, Jianmin Liu, Feng Zhou, Wei Cui, Ling Guan, Fei Shen, Cong Gao, Mufei Li, Qi Jin, Lei Gao

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 354-366 doi: 10.1007/s11684-013-0257-3

Abstract: The aim of the present study is to summarize the treatment outcomes of smear-positive pulmonary TB inResults of the present study clearly show, in general, that the pulmonary TB treatment achieved significant

Keywords： tuberculosis     treatment     outcome     China     meta-analysis    

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Perioperative management for parturients with pulmonary hypertension: experience with 30 consecutive

Lulu Ma, Wei Liu, Yuguang Huang

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 395-395 doi: 10.1007/s11684-013-0289-8

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Clinical characteristics in lymphangioleiomyomatosis-related pulmonary hypertension: an observation on

Xiuxiu Wu, Wenshuai Xu, Jun Wang, Xinlun Tian, Zhuang Tian, Kaifeng Xu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 259-266 doi: 10.1007/s11684-018-0634-z

Abstract: Knowledge on LAM-related pulmonary hypertension (PH) is limited.This study aimed to analyze the clinical characteristics of LAM with elevated pulmonary artery pressureThe study showed that LAM patients with PH exhibit poor pulmonary function and hypoxemia and may benefit

Keywords： lymphangioleiomyomatosis     pulmonary hypertension     pulmonary function     hypoxemia     sirolimus    

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Clinical characteristics of pulmonary hypertension in bronchiectasis

Lan Wang,Sen Jiang,Jingyun Shi,Sugang Gong,Qinhua Zhao,Rong Jiang,Ping Yuan,Bigyan Pudasaini,Jing He,Zhicheng Jing,Jinming Liu

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 336-344 doi: 10.1007/s11684-016-0461-z

Abstract:

Pulmonary hypertension (PH), as a complication of bronchiectasis, is associated with increased mortalityHowever, hemodynamic characteristics and the efficacy of pulmonary arterial hypertension (PAH) therapiesThe mean pulmonary arterial pressure (PAP) was 41.5±11.7 mmHg, cardiac output was 5.2±1.4L/min, and pulmonary vascular resistance was 561.5±281.5 dyn·s·cm−

Keywords： bronchiectasis     hemodynamics     pulmonary hypertension    

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Clinical characterization and diagnosis of cystic fibrosis through exome sequencing in Chinese infants

Liru Qiu, Fengjie Yang, Yonghua He, Huiqing Yuan, Jianhua Zhou

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 550-558 doi: 10.1007/s11684-017-0567-y

Abstract:

Cystic fibrosis (CF) is a fatal autosomal-recessive disease caused by mutations in the CF transmembraneCF is characterized by recurrent pulmonary infection with obstructive pulmonary disease.

Keywords： cystic fibrosis     pseudo-Bartter syndrome     hypokalemic alkalosis     CFTR gene     mutations     infants     diagnosis    

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Paeoniflorin prevents hepatic fibrosis of by inhibiting TGF-β1 production from macrophages in mice

CHU Deyong, LI Conglei, SHEN Jilong, WU Qiang

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 154-165 doi: 10.1007/s11684-008-0029-7

Abstract: In order to investigate the effect of paeoniflorin (PAE) on hepatic fibrosis of mice with and , a modelof hepatic fibrosis caused by schistosomiasis was established in mice infected with cercariae of .Hepatic granuloma and fibrosis were evaluated via HE and Masson staining. The expression of ?significantly reduce the concentration of serum HA, the size of egg granuloma, the severity of hepatic fibrosisIn a word, PAE can prevent hepatic granuloma and fibrosis caused by schistosomiasis japonica through

Keywords： cercariae     collagen     hyaluronic     OPMCM     soluble    

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mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient with cystic fibrosis

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 150-155 doi: 10.1007/s11684-021-0846-5

Abstract: Cystic fibrosis (CF) is a rare autosomal recessive disease with only one pathogenic gene cystic fibrosis

Keywords： cystic fibrosis     CFTR     splicing mutation     minigene    

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Title Author Date Type Operation

Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

ZHANG Xiaomei, JIANG Liangduo, ZHANG Wei, WU Jianjun, LU Xiangfeng

Journal Article

mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway in pulmonaryfibrosis

Li Lu, Haiyan Zhu, Hailin Wang, Huaping Liang, Yayi Hou, Huan Dou

Journal Article

Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype

Xu Chen, Xiaomao Xu, Fei Xiao

Journal Article

Survey on deep learning for pulmonary medical imaging

Jiechao Ma, Yang Song, Xi Tian, Yiting Hua, Rongguo Zhang, Jianlin Wu

Journal Article

Strategies for preventing peritoneal fibrosis in peritoneal dialysis patients: new insights based on

Zhen Zhang, Na Jiang, Zhaohui Ni

Journal Article

Expression of integrin in hepatic fibrosis and intervention of resveratrol

Jianye WU, Chuanyong GUO, Jun LIU, Xuanfu XUAN

Journal Article

Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis

Wei Gong,Mengwen Yan,Junxiong Chen,Sandip Chaugai,Chen Chen,Daowen Wang

Journal Article

Protein microspheres for pulmonary drug delivery

Yongda SUN,

Journal Article

Treatment outcomes of pulmonary tuberculosis in the past decade in the mainland of China: a meta-analysis

Xiangwei Li, Yu Yang, Jianmin Liu, Feng Zhou, Wei Cui, Ling Guan, Fei Shen, Cong Gao, Mufei Li, Qi Jin, Lei Gao

Journal Article

Perioperative management for parturients with pulmonary hypertension: experience with 30 consecutive

Lulu Ma, Wei Liu, Yuguang Huang

Journal Article

Clinical characteristics in lymphangioleiomyomatosis-related pulmonary hypertension: an observation on

Xiuxiu Wu, Wenshuai Xu, Jun Wang, Xinlun Tian, Zhuang Tian, Kaifeng Xu

Journal Article

Clinical characteristics of pulmonary hypertension in bronchiectasis

Lan Wang,Sen Jiang,Jingyun Shi,Sugang Gong,Qinhua Zhao,Rong Jiang,Ping Yuan,Bigyan Pudasaini,Jing He,Zhicheng Jing,Jinming Liu

Journal Article

Clinical characterization and diagnosis of cystic fibrosis through exome sequencing in Chinese infants

Liru Qiu, Fengjie Yang, Yonghua He, Huiqing Yuan, Jianhua Zhou

Journal Article

Paeoniflorin prevents hepatic fibrosis of by inhibiting TGF-β1 production from macrophages in mice

CHU Deyong, LI Conglei, SHEN Jilong, WU Qiang

Journal Article

mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient with cystic fibrosis

Journal Article